I've been fighting crickets with low yellow bile and blood (under 10). I sometimes replenish Humour in between hits. When I do I always get an error message telling me I don't "have enough resources" as if I was crafting something.
I've been using the Ender client so I'm not sure if it's strictly Ender or if this happens on Vanilla too. I currently don't need to kill crickets and will not rush to check this on Vanilla.